Topical delivery of long-acting antiretrovirals to prevent HIV acquisition
نویسندگان
چکیده
منابع مشابه
Long-acting injectable antiretrovirals for HIV treatment and prevention
PURPOSE OF REVIEW Long-acting antiretroviral (ARV) drugs may improve adherence to therapy and extend opportunities for therapeutic or prophylactic intervention to underserved patient populations. This review focuses on recent advances in the development of small molecule long-acting injectable ARV agents. RECENT FINDINGS The need for combination ART and physicochemical and dosing limitations ...
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There is a clear convergence toward an overarching strategic use of antiretroviral drugs to prevent human immunodeficiency virus (HIV) infection. Four interventions-immediate antiretroviral therapy (ART) for the infected partner in a serodiscordant couple, preexposure prophylaxis (PrEP), prevention of mother-to-child transmission (PMTCT), and postexposure prophylaxis (PEP)-are all strongly reco...
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PURPOSE OF REVIEW Long-acting injectable antiretroviral (ARV) formulations are being developed for the treatment and prevention of HIV infection. The purpose of this review is to summarize recent preclinical and clinical data on TMC278 (rilpivirine), a nonnucleoside reverse transcriptase inhibitor (NNRTI), that is being developed for both a treatment and prevention indication. RECENT FINDINGS...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2020
ISSN: 1746-630X
DOI: 10.1097/coh.0000000000000598